Performance Analysis of Absorption Refrigeration Cycles

The thermodynamic analysis of a vapor absorption refrigeration system employing ammonia as the refrigerant are presented. The thermodynamic analysis of these three combination of the absorption pairs namely NH3/H2O, NH3/LiNO3, NH3/NaSCN are performed. The best alternative to the ammonia water absorption pair are proposed as ammonia lithium nitrate and ammonia- sodium thiocyanate. It is very much important to select a prominent working substance and their properties have great effect on the system performance. Detailed thermodynamic properties of these fluids are expressed in polynomial equations. Energy and entropy balance equations are applied to analyse each of the process to estimate the individual heat transfer and entropy generation rates for all the systems. Among these three pairs NH3/ NaSCN yields the highest coefficient of performance. Cooling/Heating of the generator/absorber results in significant entropy generation in all the systems. The solution heat exchanger significantly improves the performance of the cycle and yields in the better cooling output

PROVIDING THE BOUNDARY LINE CONTROLLED REQUEST WITH ADAPTABLE TRANSMISSION RATES IN WDM MESH NETWORKS

The mixture of applications increases and supported over optical networks, to the network customers new service guarantees must be offered .The partitioning the data into multiple segments which can be processed independently the useful data to be transferred before a predefined deadline .this is a deadline driven request. To provide the request the customer chooses the bandwidth DDRs provide scheduling flexibility for the service providers. It chooses bandwidth while achieving two objectives 1.satisfying the guaranteed deadline 2.decreasing network resource utilization .by using bandwidth allocation policies improve the network performance and by using mixed integer linear program allows choosing flexible transmission rates

Scope of Manuscriptology in Ayurveda

Manuscriptology is the scientific or structural study of handwritten document credited with fair antiquity. Not even 5% of the available manuscripts in our country have been brought into limelight. National manuscript mission’s study reveals the fact that, more than 20000 Ayurvedic manuscripts are identified but still unexplored. Here lies an extensive scope for Ayurveda in the field of Manuscriptology. As no complete catalogue of Indian medical manuscripts are available till date, the treasure of knowledge which lie hidden in oriental libraries and private custodies can be brought into mainstream by the well-organized steps of Manuscriptology - collection, conservation, cataloguing, transcription, translation, critical edition and publication. Of late, it is observed that some of the Ayurvedic scholars are involving in manuscript studies and institutions are supporting the preservation of ancient knowledge, but such works aims at a level of individual study rather than an organized one. Collaboration of various scholars of Ayurveda and languages like Sanskrit along with many experts in this field should be brought together to accomplish the task of publication of manuscripts. Only 2% of medical manuscripts are in printed form, so initiation should be taken up for the conservation, cataloguing, critical edition, and publication of Ayurvedic manuscripts which will open a new way for further activities in research area of Ayurveda including effective clinical researches

STUDIES ON THROMBOLYTIC AND ANTI-HELMINTIC ACTIVITY OF Cocccinea grandis

Traditional system of medicine consists of large number of plants with various medicinal and pharmacological values and hence represents a priceless tank of new bio active molecules. Coccinea grandis belongs to the family Cucurbitaceae, is a rapidly growing, perennial climber or trailing vine. Traditionally different parts of this plant namely roots, leaves, and fruits are used in folklore medicine for several purposes like jaundice, diabetes, wound healing, ulcers, stomach ache, skin disease, fever, asthma, cough. Development of anthelmintic resistance and high cost of conventional anthelmintic drugs led to the evaluation of medicinal plants as an alternative source of anthelmintics.  As no scientific data was available on this plant hence, the present study was carried out for the investigation of antihelmintic activity and thrombolytic activity of bark of Coccinea grandis. Antihelmintic activity was done on pheritima posthuma. The results obtained were compared with standard albendazole and control groups respectively, the parameters evaluated are time of paralysis and time of death. On the other hand thrombolytic activity was done by using aqueous extract of Coccinea grandis bark. Thrombi or emboli can lodge in a blood vessel and block the flow of blood in that location depriving tissues of normal blood flow and oxygen. This can result in damage, destruction (infarction), or even death of the tissues (necrosis) in that area. Streptokinase is an antigenic thrombolytic agent used for the treatment of acute myocardial infarction, served as standard. This study was conducted on human blood sample and compared with standard and control groups respectively. The parameters studied are percentage of clot lysis. From the present study we found that various extracts of this plants showed significant thrombolytic and antihelmintic properties.Key words: thrombolysis, helminthes, coccinea, albendazole, streptokinase

Effect of Humic Acid on Spirulina plantisis Production and Analysis of Nutrient Contents

Spirulina is a microscopic blue-green alga in the shape of a spiral coil, used as a human dietary supplement, as well as a whole food, which was cultivated in different concentrations of humic acid such as 0.1%, to 0.7 %. The protein, chlorophyll, fatty acids levels measured at the end of the experiment in all concentrations. Among the concentration the maximum biomass was obtained from 0.2% of humic acid treated medium. The lower amount of biomass was obtained from above 0.5%.In this study, it was found that increased concentration of humic acid decreases the biomass of Spirulina plantensis. Thus it was concluded in this work, that lower concentration of humic acid increases the growth and nutrient contents of Spirulina plantensiss

Early Investigations and Recent Advances in Intraperitoneal Immunotherapy for Peritoneal Metastasis.

Peritoneal metastasis (PM) is an advanced stage malignancy largely refractory to modern therapy. Intraperitoneal (IP) immunotherapy offers a novel approach for the control of regional disease of the peritoneal cavity by breaking immune tolerance. These strategies include heightening T-cell response and vaccine induction of anti-cancer memory against tumor-associated antigens. Early investigations with chimeric antigen receptor T cells (CAR-T cells), vaccine-based therapies, dendritic cells (DCs) in combination with pro-inflammatory cytokines and natural killer cells (NKs), adoptive cell transfer, and immune checkpoint inhibitors represent significant advances in the treatment of PM. IP delivery of CAR-T cells has shown demonstrable suppression of tumors expressing carcinoembryonic antigen. This response was enhanced when IP injected CAR-T cells were combined with anti-PD-L1 or anti-Gr1. Similarly, CAR-T cells against folate receptor α expressing tumors improved T-cell tumor localization and survival when combined with CD137 co-stimulatory signaling. Moreover, IP immunotherapy with catumaxomab, a trifunctional antibody approved in Europe, targets epithelial cell adhesion molecule (EpCAM) and has shown considerable promise with control of malignant ascites. Herein, we discuss immunologic approaches under investigation for treatment of PM

A Review on Smart Cart Shopping System Using IOT

The internet of things (IOT) is changing human lives by connecting everyday objects together. Nowadays shopping at big malls is a daily activity in metro cities. One can see a huge rush at malls on holidays and on special discount days. People purchase different items and put them in trolleys and go to billing counter for payments. In that time, they have to wait in a long queue to get their products scanned using RFID reader with help of barcode scanner and get their billed. To modify that customer has to purchase in smart way in shopping malls. Each and e very product is attached with a RFID tags, when placed into a smart shopping cart, can be automatically read by a cart equipped with a RFID reader, so that the billing can be conducted from the shopping cart itself. In this way, customer can avoid waiting in a long queue at the checkout points. For this system, additional smart shelving can be added and equipped with RFID reader and can monitor stock, also updating central server, server knows the status of the items in the store. The inventory management also becomes much easier, because all the items can be automatically read by a RFID reader instead of manually scanned by the laborer

Nutritional requirement at high-altitude with special emphasises to behaviour of gastro-intestinal tract and hormonal changes

When people are exposed to the extreme environmental conditions, such as high altitude (HA) where there is decrease in temperature and partial pressure of oxygen induces fatigue, insomnia, loss of appetite and increased cardiac output. Hence there is need to improve the appetite through the diet and digestion clout of the individual. In the present review paper we have discussed the efficiency of digestion is compromised at HA. Also about, Hypoxia, resulting by decreased partial pressure of oxygen can be classified into acute hypoxia and chronic hypoxia based on the exposure time. There is increased formation of reactive oxygen species (ROS) due to less oxygen available in the air at HA which leads to oxidative stress. Lipid peroxidation caused by oxidative stress. Hypoxia is mediated through hypoxia inducible factors which maintain oxygen haemostasis in the body. At HA diet rich in carbohydrates have been found to be beneficial as it increases glucose metabolism. Requirement of nutrients such as vitamin A, vitamin E and vitamin C as well as micronutrients such as zinc, iron, selenium, copper and manganese will be required at HA. Hypoxia effect on the intestine leads to malabsorption and the lipid storage is stimulated and lipid catabolism is inhibited through β-oxidation

Biodecolorization and biodegradation of Reactive Blue by Aspergillus sp.

Aspergillus sp. effectively decolorized Reactive Blue and other structurally different synthetic dyes. Agitation was found to be an important parameter, while glucose (99%), sucrose (97%) and mannitol (98%) were the best carbon sources for the decolorization. Decolorization was effective in an acidic environment (pH 3). Few chemically different dyes such as Reactive Black (75%), Reactive Yellow (70%), Reactive Red (33%) and Coloron Violet (66%) were decolorized moderately.The dye Coloron Black (9%)was highly resistant for decolorization by Aspergillus sp. Both spectral analysis and HPLC analysis were confirmatory to degradation